Charles Brenton Huggins
Physician and researcher, University of Chicago from 1927
- Dates
- 1901-1997 (source: Nobel Prize: Charles B. Huggins, biographical )
- Chapters
- IX. The Gland That Stands Before
What the film says
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Isolated the dog prostate and measured its secretion, which stopped after castration, returned with testosterone and stopped with oestrogen.
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With Hodges in 1941, showed that castration or oestrogen lowered acid phosphatase and eased pain in advanced prostate cancer; shared the Nobel Prize in 1966.
On the timeline
- 1939: Huggins and colleagues isolate the dog prostate and measure its secretion over months (J Exp Med). timeline
- 1941: Huggins and Hodges report that castration or oestrogen lowers, and androgen raises, serum phosphatases in metastatic prostate cancer (Cancer Research). timeline
- 1941: Huggins, Stevens and Hodges report the effects of castration on advanced prostate cancer (Archives of Surgery). probable timeline
- 1966: Huggins shares the Nobel Prize in Physiology or Medicine with Peyton Rous; his Nobel lecture is given on 13 December. timeline
Sources
Sources
- Nobel Prize: Charles B. Huggins, biographical Secondary
- Wikipedia: Charles Brenton Huggins Secondary
- Huggins, Masina, Eichelberger and Wharton 1939, Quantitative studies of prostatic secretion I (J Exp Med 70:543) Primary
- Huggins, Nobel lecture, 13 December 1966 Primary
- Nobel Prize in Physiology or Medicine 1966: summary Secondary